概述  

三维人体组织仿电磁真软件平台Sim4Life 是由瑞士IT'IS基金会研发的，已获得瑞士CTI医疗科技奖，Sim4Life平台结合可计算人类模型、物理解算器和先进的组织模型，能直接分析人体真实世界和复杂技术设备，以及验证人体和解剖学环境之中的变化。Sim4Life采用高性能计算和最直观GUI架构，能实现精确的多物理模擬，和无尽的定制加快研发活动，协助医疗及科研团队优化医疗器械和治疗方法，且同時符合最安全性和有效性的要求。
    三维人体组织电磁仿真软件平台Sim4Life运作流程可分成MRI/CT 3D影像重建、解剖及产品模型导入(CAD)、多样化解算器、组织和物理模型、直观的分析报告及硬体验证等阶段，能够在取得多张影像资料之后，快速进行完整3D三维影像重建，再利用內建产品模型，产生接近真实狀況的模擬资料。而且产品本身支持市面上常見的模型软件，包含各种公开的人体解剖模型，绝对能够符合不同医疗环境的使用需求。
      三维人体组织电磁仿真软件平台Sim4Life內建为计算复杂问题所设计的运算核心，包括EM、热学、声波和流体求解，医疗研究单位只要安裝在高效能电脑上，即可在最短時间內获得运算結果。此外，三维人体组织仿真软件平台Sim4Life本身便有灌注模型，组织损伤模型和神经元模型，均是現今手术过程中使用頻率最高的元件，特別是软件本身可透过简单易于操作的图形化三维介面，协助操作者完成定义问题、离散，模擬和分析等步骤，能让模擬結果都更接近真实結果。
      一般來说，健康管理平台上收集到的资料有兩大用途，首先是作为医生治疗前的评估參考，如用药种类或是手术形式，其次則是将病历资料转换为更容易阅读的可视化图像。医院或研究单位若能够将前述两类资料，输入到多重物理模擬软件Sim4Life時，則有助于新医疗技术开发，进而为特定疾病研发出更有效的药物或治疗工具。

In silico

The digital revolution is extending the frontiers of medicine and medical technology. Computer modeling and simulation (CM&S), or in silico technologies, merge computational tools with biology to intuitively, precisely, and reproducibly perform complex analyses of life sciences applications.  With this emerging paradigm, experimental manipulations that are infeasible or impossible to conduct in real-life experiments can be created while maintaining experimental control: the perfect complement to in vivo and in vitro studies.

ZMT provides in silico solutions to the medical device industry. Our comprehensive simulation platform, Sim4Life, provides a powerful 3D validated biological and anatomical modeling environment for optimizing the effectiveness and performance of medical devices, improving patient safety, and discovering potential new treatments. Built from the ground up, Sim4Life provides smooth and fully automated or customizable workflows for applications ranging from exploratory research and medical device development to regulatory documentation for clinical trials and device certification.

we trust

Our software tools are thoroughly and continually verified to ensure their reliability and performance requirements as they evolve.

The same effort is on validation for our expanding portfolio of targeted life sciences models and applications.

ZMT also provides test systems for validation procedures that support complex requirements with software tools optimized for test and measurement systems.

At ZMT, we leverage the combined strength of our expertise, experience, cost-effective solutions, and commitment to long and fruitful client relationships to enhance your competitive advantage during the regulatory submission process.
Phantoms                                                       Solvers & Tissue Models                         Validation Hardware

     

Sim4Life

Sim4Life is the first computational life sciences platform integrating computable human phantoms with the most powerful physics solvers and the most advanced tissue models for directly analyzing biological real-world phenomena and complex technical devices in a 3D validated biological and anatomical environment.

At the core of Sim4Life are the computable, high-fidelity 3D Virtual Population (ViP) human anatomical models. Carefully selected to fully represent global variations in human anatomy, the fully posable, morphable, and validated ViP models along with the IT'IS tissue properties database depict 15 different body types with 120 vital anatomical features and over 300 precisely identified tissues and organs. Cited and applied in hundreds of published studies and papers, the ViP models and the IT'IS material parameter database are continually and meticulously updated, refined, and expanded.

Sim4Life is a revolutionary simulation platform, combining computable human phantoms with the most powerful physics solvers and the most advanced tissue models, for directly analyzing biological real-world phenomena and complex technical devices in a validated biological and anatomical environment. The Sim4Life platform also offers leading performance with all the features expected from a multiphysics CAE/TCAD platform. Watch the Sim4Life demo video!

Computable Human Phantoms                                                                 Physics Solvers 
       

Sim4Life natively supports the Virtual Population ViP 3.0 models that include integrated posing and morphing tools. Other publicly available animal and human anatomical models are also supported. All tissues are linked to a continually updated physical properties database.

The powerful Sim4Life solvers are specifically developed for computationally complex problems; HPC accelerated for the latest computer clusters; and smoothly integrated in the most advanced coupling framework. The platform already includes EM, Thermal Acoustic, and Flow solvers.

Tissue Models                                                                                      Framework
        

The integrated tissue models enable the modeling and analysis of physiological processes. Perfusion models, tissue damage models, and neuronal models are already included in the first release of Sim4Life.

The Sim4Life Framework efficiently facilitates all steps in complex multiphysics modeling, from defining the problem, discretizing, simulating, and analyzing to visualizing the results, with clarity and flexibility.

Sim4Life Platform 三维人体组织电磁仿真软件平台Sim4Life组成

Computable Human Phantoms 可计算人类仿真软件	Physics Models   物理模型	Tissue Models   组织模型	Intuitive GUI and Workflow 直观的图形用户界面及集成平台	Licensed Modules   可授权模块
ViP 3.0 Virtual Population	P-EM-FDTD Electromagnetics Full Wave Solvers	T-NEURO Neuronal Tissue Models	iSEG Medical Image Segmentation Tool Set	MRI M-MUSAIK M-TxCOIL M-BCAGE M-SYSSIM M-GRAD M-IMSAFE
ViA 1.0 Animal Models	P-EM-QS Quasi-Static Electromagnetics Solvers	T-CEM43 Tissue Damage Models	MODELER Advanced Modeling Tool Set
Third-Party Models	P-THERMAL Thermodynamics Solvers	T-FLOWRATES Flow Rate Computational Engine	MESHER Robust & Effective Meshing	MODELING M-REMESH M-POSER
	P-FLOW Fluid Dynamics Solvers		ANALYZER Versatile Postprocessor and Analyzing Tool Set	CALCULATORS M-DISPFIT M-PPCALC
	P-ACOUSTICS Acoustics Solvers		PYTHON Control via Python Scripting	PROCESSING M-MATCH M-TALATLAS M-MBSAR M-PHARRAY
	P-CRD Convection Reaction Diffusion Solvers (coming soon)
	P-MECH Mechanical Solvers (coming soon)			IMPORT M-HUYGENS M-IMG M-VOX
	High Performance Computing Auto-Scheduler & Control ARES

Computable Human Phantoms-ViP 3.0 可计算三维人体组织仿真软件-ViP 3.0
Physics Models 物理模型
Tissue Models 组织模型
Framework - Intuitive GUI and Workflow直观的图形用户界面及集成平台
Sim4Life Modules - Licensed Modules可授权模块
Configurations配置

完整产品资料请通过链接下载：三维人体组织电磁仿真软件平台 Sim4Life.pdf